slot slot gacor slot gacor slot deposit 5000 mariatogel88 gaspol777 Kongbet268 HKG999 menara88 kongbet268 777w rp55 888R SL999 GG999 SL88 8II RP99 RK88 KONGBET268 slot gacor slot 5k Journal Title: Jurnal Sains dan Kesehatan Initials: JUSIKA Frequency: Juni dan Desember Print ISSN: 2580-8362 Online ISSN: 2962-1569 Editor in Chief: Ns. Bayu Dwi Setyo. S.Kep.,M.Kep DOI: 10.57214 Publisher: LPPM Universitas Muhammadiyah Manado Jurnal Sains dan Kesehatan (JUSIKA) merupakan publikasi ilmiah dalam konten kesehatan dan sains yang memuat hasil penelitian, kajian pustaka, analisis kritis dan pengembangan. Terbit pertama kali tahun 2017 berdasarkan SK Nomor. 0005.25808362/JI.3.1/SK.ISSN/2017.07 dengan nomor ISSN Cetak : 2580-8362 dengan frekuensi terbitan sebanyak dua kali dalam setahun pada bulan Juni dan Desember. Artikel yang dipublikasikan dalam jurnal ini sudah melewati proses evaluasi dan penyntingan oleh dewan redaksi. Jurnal Kesehatan dan Sains terbuka untuk umum, peneliti, pegawai dan pemerintah. Jurnal ini terakreditasi SINTA 4 (SK Direktur Jenderal Pendidikan Tinggi, Riset, dan Teknologi Nomor 156/C/C3/KPT/2026 tanggal 7 April 2026, tentang Pemberitahuan Hasil Akreditasi Jurnal Ilmiah Periode 2 Tahun 2025), dimulai dari Volume 7 Nomor 1 Tahun 2023 sampai Volume 11 Nomor 2 Tahun 2027.. Indexed by : Journal Sponsors and Partners :
Hubungan Riwayat Berat Badan Lahir Rendah Dengan Kejadian Stunting Pada Anak Balita Usia 2-5 Tahun Di Puskesmas Bandarharjo Semarang
Stunting remains a significant nutritional issue because it can impact a child's long-term growth and development. A history of low birth weight (LBW) is suspected to play a role, reflecting the condition of fetal growth during pregnancy. This study aimed to determine the relationship between a history of LBW and the incidence of stunting in children aged 2–5 years at the Bandarharjo Community Health Center in Semarang in 2025. This study used an analytical design with a case-control approach. The study sample consisted of 203 toddlers selected using consecutive sampling. Data were obtained from the KIA book and height measurements based on WHO standards. Analysis was performed using the Chi-Square test and Odds Ratio (OR) calculation. The proportion of LBW was 10.8% and stunting was 31.0%. There was a significant relationship between a history of LBW and the incidence of stunting (p = 0.012). Toddlers with a history of LBW had approximately a threefold greater risk of experiencing stunting compared to toddlers born with normal weight (OR = 3.059). There is a relationship between a history of low LBW and the incidence of stunting in toddlers aged 2-5 years at the Bandarharjo Community Health Center, Semarang in 2025.
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Gambaran Ct Value pada Swab Pertama dan Swab Kedua Covid 19 pada Anak di Indramayu
Corona Virus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The first case was identified in Wuhan, China, in December 2019. The World Health Organization declared COVID-19 a Public Health Emergency of International Concern (PHEIC) on January 30, 2020, and a pandemic on March 11, 2020. This study aimed to determine the results of CT Value images on the first and second swab tests of children with COVID-19 in Indramayu. A descriptive design was used with total sampling, involving 54 respondents. Secondary data were analyzed using univariate analysis. On the first swab test, 27 children (50.0%) had a strong positive Ct Value, 26 children (48.1%) were positive, and 1 child (1.9%) had a weak positive Ct Value. On the second swab test, 23 children (71.9%) were positive, 6 children (18.8%) were strong positive, and 3 children (9.4%) were weak positive. All children tested positive on the first swab, while 32 (59.3%) remained positive and 22 (40.7%) became negative on the second swab. Most children showed decreased infection severity, although some remained positive.
Faktor-Faktor yang Berhubungan dengan Kesiapan Kader Posyandu ILP di Wilayah Kerja Puskesmas Penusupan Kabupaten Tegal Tahun 2026
The Integrated Primary Care Posyandu (ILP) program requires cadres to assume a much broader role compared to conventional Posyandu services. In the working area of Puskesmas Penusupan, ILP achievement reached only 20% in 2025, while merely 25 out of 225 cadres (11%) had received related training. This condition indicates that cadre readiness needs to be examined more comprehensively before the program can be implemented optimally. This study aimed to analyze the factors associated with the readiness of ILP Posyandu cadres using a descriptive-analytic method with a cross-sectional approach. The study involved 144 cadres selected proportionally from a population of 225 using the Slovin formula. Data were collected through structured interviews using a validated questionnaire and analyzed using univariate, bivariate (Spearman Rank), and multivariate (ordinal logistic regression) analyses. The results showed that among the eight variables examined, only skills (r = 0.171; p = 0.040) and resource availability (r = 0.225; p = 0.007) were significantly associated with cadre readiness. In the multivariate analysis, resource availability emerged as the most influential factor with an OR = 2.839 (95% CI: 1.311–6.149), indicating that cadres supported by adequate resources were 2.8 times more likely to demonstrate good readiness. In conclusion, resource availability was identified as the dominant factor associated with the readiness of ILP Posyandu cadres in the working area of Puskesmas Penusupan. Therefore, improving the availability of facilities and infrastructure, providing practice-based training, and strengthening operational support should become priority programs in the future.
Prevalensi Rinosinusitis Kronik di Poliklinik THT-KL RSUD dr. Doris Sylvanus Kota Palangka Raya Tahun 2023 dan 2024
Chronic rhinosinusitis (CRS) is a long-term inflammatory condition affecting the nasal mucosa and paranasal sinuses, which significantly impacts patients’ quality of life due to persistent and recurrent symptoms. Limited epidemiological data regarding CRS are available in Central Kalimantan, particularly at RSUD dr. Doris Sylvanus in Palangka Raya, prompting this study to determine its prevalence and patient distribution characteristics. This research employed a quantitative descriptive design with a cross-sectional approach. Data were collected from medical records of patients diagnosed with CRS in 2023 and 2024. Univariate analysis was conducted, and results were presented in tables and diagrams illustrating frequency distributions by year, gender, age, and main complaints. The findings showed a total of 118 CRS patients, with 53 cases in 2023 and 65 cases in 2024. The prevalence of CRS increased from 4.91% in 2023 to 10.83% in 2024. Based on gender, males accounted for 50.8% (60 patients), while females represented 49.2% (58 patients). The age group most affected was 46–55 years (31%), indicating a predominance among individuals of productive age. Nasal congestion was the most frequent primary complaint, reported by 35% of patients. The study concludes that the prevalence of CRS at RSUD dr. Doris Sylvanus increased notably from 2023 to 2024, with a slightly higher incidence among males in the productive age group. These findings highlight the need for enhanced preventive measures and early diagnosis to manage CRS more effectively in the local population.
Pengaruh Usia, Gender dan Kedekatan Tempat Tinggal dengan Landfill terhadap Kejadian Diabetes Melitus Tipe 2
Diabetes Mellitus is a non-communicable disease with an increasing prevalence and has become a major public health concern globally and nationally. The incidence of diabetes mellitus is influenced by various individual and environmental factors. This study aimed to analyze the relationship between age, gender, and residential proximity to landfill areas and the incidence of diabetes mellitus in Bendosari District. A quantitative analytic observational design with a cross-sectional approach was employed. The study population consisted of 1,890 patient visit records recorded in the Management Information System of Bendosari Public Health Center in 2025. A total of 363 respondents were selected using proportionate stratified random sampling. Data were analyzed through univariate analysis, bivariate analysis using the Chi-Square test, and multivariate analysis using multiple logistic regression. The findings showed that age was significantly associated with diabetes mellitus incidence (p=0.000; OR=79.790; 95% CI=53.511–118.974). Gender was also significantly related to diabetes mellitus incidence (p=0.000; OR=0.298; 95% CI=0.203–0.435), indicating that females had a higher risk than males. In contrast, residential proximity to landfill areas was not significantly associated with diabetes mellitus incidence (p=0.308; OR=1.247; 95% CI=0.439–3.540). Multivariate analysis revealed that age and gender were the dominant factors influencing diabetes mellitus incidence, with the model explaining 56.1% of the variation. The study concludes that age and gender are significant determinants of diabetes mellitus incidence, whereas residential proximity to landfill areas has not been proven to significantly affect its occurrence.
Hubungan Hipertofi Adenoid Berdasarkan Rasio Adenoid-Nasofaring Dengan Kejadian Otitis Media
Background: Adenoid hypertrophy is a condition characterized by enlargement of the adenoid tissue which can cause nasopharyngeal obstruction and potentially affect the function of the Eustachian tube. Dysfunction of the Eustachian tube may disrupt middle ear ventilation and increase the risk of otitis media. The degree of adenoid hypertrophy can be objectively assessed using a lateral nasopharyngeal radiograph by calculating the adenoid–nasopharyngeal ratio (A/N ratio). Objective: This study aimed to determine the relationship between adenoid hypertrophy based on the adenoid–nasopharyngeal ratio and the incidence of otitis media. Methods: This study was a quantitative research with an analytic observational design using a cross-sectional approach. Data were obtained from the medical records of patients with adenoid hypertrophy who underwent lateral nasopharyngeal radiographic examination at RSI Purwokerto from 2022 to 2025. The sample consisted of 31 patients who met the inclusion and exclusion criteria. Data analysis was performed using the Spearman correlation test because the data were not normally distributed based on the Shapiro–Wilk test. Results: The results showed that most of the subjects were male (17 subjects, 54.8%) and female (14 subjects, 45.2%). The median age of the subjects was 7 years with an age range of 4–9 years. The median adenoid–nasopharyngeal ratio was 0.90 with a range of 0.68–0.99. Otitis media was found in 11 subjects (35,5%), while 20 subjects (64,5%) did not experience otitis media. The Spearman correlation test showed a correlation coefficient of r = 0.015 with a p-value of 0.936 (p > 0.05), indicating that there was no significant relationship between the adenoid–nasopharyngeal ratio and the incidence of otitis media. Conclusion: There was no statistically significant relationship between adenoid hypertrophy based on the adenoid–nasopharyngeal ratio and the incidence of otitis media.
Pengaruh Terapi Aktivitas Kelompok Art Painting terhadap Tingkat Sters pada Lansia di Panti Sosial Tresna Werdha Budi Mulia 2 Cengkareng
Stress in older adults needs attention because it can negatively affect physical, emotional, and social well-being, as well as overall quality of life. Elderly individuals living in social welfare institutions are particularly vulnerable to stress due to environmental changes, limited family involvement, loneliness, daily routines, and reduced independence. This study aimed to determine the effect of art painting group activity therapy on stress levels among older adults at Budi Mulia 2 Cengkareng Social Welfare Home. A quantitative pre-experimental study with a one-group pretest-posttest design was conducted involving 33 participants selected through total sampling. Stress levels were measured using the DASS-21 stress subscale. The intervention consisted of four art painting sessions lasting 30–45 minutes each. Data were analyzed using the Wilcoxon test. The mean stress score decreased from 22.18 before the intervention to 15.94 after the intervention. The Wilcoxon test showed a significant difference (p = 0.000), indicating that art painting group activity therapy effectively reduced stress levels among older adults.
Pentingnya Asupan Gizi Seimbang untuk Meningkatkan Performa Atlet Muda: Perspektif dan Edukasi bagi Orang Tua Atlet di SSB Kancil Mas
Balanced nutrition intake is an important factor in supporting the performance of young athletes, especially during the growth period that requires optimal nutrition for intense physical activity. However, the lack of nutritional knowledge among parents of young athletes often leads to nutritional imbalances that have a negative impact on athlete health and performance. This study aims to measure the effect of balanced nutrition education on improving the knowledge and attitudes of parents of athletes at the Kancil Mas Football School (SSB), Karawang. The method used was a quasi-experiment with a pre-test and post-test design involving 20 respondents who were parents of U-13 athletes. Education was provided in the form of direct counseling sessions and group discussions, which were supplemented with supporting materials such as leaflets. The Wilcoxon signed rank test was used to analyze changes in parental knowledge and attitude scores before and after the intervention. The results of the analysis showed a significant increase in parents' understanding and positive attitudes towards balanced nutrition after education (p < 0.05). The results showed a significant increase in the level of parents' understanding and positive attitudes towards nutrition after the education intervention. These findings highlight the importance of active parental involvement in ensuring that young athletes' nutritional needs are met, as well as providing a basis for developing nutrition education programs in other sports schools.
Bibliometric Analysis of Trends in Risk Factors in Melasma
Risk factors for melasma have been identified at several points such as the use of birth control pills, cosmetics, sun exposure, estrogen therapy, decreased thyroid and ovarian function, ovarian tumors, nutrition, drugs that are classified as phototoxic or photoallergic, and epilepsy drugs. This article aims to determine the incidence of melasma and its risk factors. This study uses articles collected from the Google Scholar database. The data collection step uses the keyword "Risk Factor Melasma" according to the title and keyword criteria. The articles used are publications in the 2018-2023 year range. The stages of analysis are carried out using VOSviewer software for visualization and trend analysis in the form of bibliometric maps. The bibliometric approach was applied to identify publication patterns, research developments, and relationships among topics related to melasma risk factors. Based on the visualization results, 100 selected documents were published within 5 years, from 2018 to 2023. The findings provide an overview of the main research trends and contribute to a better understanding of the incidence of melasma and the factors associated with its occurrence
Eksplorasi Senyawa dan Efek Ekstrak Daun Sirsak (Annona muricata L.) terhadap Viabilitas dan Ekspresi Gen BCL2 pada Sel HeLa
Human Papillomavirus (HPV) infection is typically the cause of cervical cancer, one of the cancers with a high death rate among women. Despite their widespread use, conventional therapeutic approaches still have drawbacks, such as the emergence of cancer cell resistance and severe side effects. Natural compounds are now used as safer alternative treatments as a result. Soursop leaves (Annona muricata L.) are one plant that has been shown to have anticancer potential. Through phytochemical screening, compound identification using GC-MS, cell viability testing using the MTT Assay, and BCL2 gene expression analysis using qPCR, this study attempts to examine the potential of soursop leaf extract as an anticancer agent against cervical cancer cells (HeLa cells). The results of the phytochemical examination showed that steroids, phenolics, and alkaloids were present. Ostole, bisacumol, and ricinoleic acid were found to be the predominant components when the active chemicals were identified by GC-MS. With an IC²₀ value of 5.01 μg/mL, the MTT experiment demonstrated that soursop leaf extract could decrease cell viability as the concentration rose. Furthermore, BCL2 gene expression was significantly reduced, especially in treatments with doses of 500 and 1000 μg/mL, according to the results of qPCR gene expression analysis. The overall findings suggest that soursop leaf extract may be used as a natural anticancer treatment against HeLa cells by lowering the expression of the BCL2 gene.
Hubungan Stress dan Obesitas dengan Gangguan Pola Menstruasi pada Remaja Siswi SMAN 1 Majene Tahun 2026
Background: Menstruation is a natural physiological process that indicates the functional maturity of the female reproductive system. Menstrual cycle disorders can be influenced by several factors, including stress and obesity. Stress may cause hormonal changes through the hypothalamic-pituitary axis, leading to decreased luteinizing hormone (LH) levels and menstrual irregularities. Obesity can also affect ovarian function and disrupt the menstrual cycle. Objective: To determine the relationship between stress and obesity with menstrual cycle disorders among female adolescents at SMAN 1 Majene in 2026. Methods: This study used an analytical observational design with a cross-sectional approach. Data on stress levels, obesity status, and menstrual cycle disorders were collected simultaneously from 84 female respondents. The chi-square test was used to analyze the relationships among variables. Results: The analysis showed a significant relationship between stress and menstrual cycle disorders (p = .006; α < .05). A significant relationship was also found between obesity and menstrual cycle disorders (p = .002; α < .05). Many obese respondents experienced irregular menstrual cycles. Conclusion: There is a significant relationship between stress and obesity with menstrual cycle disorders among female adolescents at SMAN 1 Majene.
Association of Circulating Tumor DNA (ctDNA) to Monitoring Treatment Response in Urothelial Carcinoma: A Comprehensive Systematic Review
Circulating tumor DNA (ctDNA) has emerged as a promising liquid biopsy biomarker for real-time monitoring of tumor dynamics. In urothelial carcinoma (UC), effective monitoring of treatment response remains a clinical challenge due to the limitations of conventional imaging and invasive procedures. This systematic review aims to synthesize the existing evidence on the association between ctDNA dynamics and treatment response monitoring across various stages and therapeutic settings. A comprehensive systematic review was conducted. We included cohort studies, randomized controlled trials, and meta-analyses that evaluated ctDNA in UC patients undergoing treatment. Data were extracted on patient population, methodology, treatment, sampling strategy, clinical outcomes, and statistical associations. The review encompassed 80 studies. Baseline ctDNA positivity was strongly prognostic, associated with a 4- to 6-fold increased risk of recurrence or death (HR 4.23-6.56). Dynamic ctDNA clearances or significants reduction during treatment, were strongly associated with improved outcomes. Showing hazard ratios for adverse events as low as 0.10-0.31. ctDNA demonstrated time advantages of 53-90 days over radiographic detection. ctDNA is a potent tool for monitoring treatment response in urothelial carcinoma. It provides superior prognostic and offers a significant lead time for detecting treatment failure. Future research must focus on standardizing methodologies and validating ctDNA-guided therapeutic.
Formulasi, Evaluasi, dan Uji Aktivitas in Vivo Kapsul Ekstrak Daun Pepaya California (Carica papaya L.) pada Model Zebrafish
California papaya leaves (Carica papaya L.) are known to contain various active compounds that have the potential to stimulate appetite and boost metabolism, making them a promising candidate for development as a pharmaceutical formulation. This study aims to design a capsule formulation of California papaya leaf extract with appropriate excipients and to evaluate its ability to increase body weight through preclinical testing using a zebrafish (Danio rerio). The extract was obtained via maceration with 96% ethanol and formulated into capsules using the wet granulation method in four variations (F0–F3). Physical evaluations included organoleptic properties, flowability, angle of repose, loss on drying, disintegration time, weight uniformity, and stability testing using the cycling test method. The results indicated that all formulas met the physical requirements, with disintegration times of 3–4 minutes and loss on drying <15%. Formula F2 exhibited the most optimal physical characteristics; however, stability testing revealed a decline in physical properties after extreme temperature treatment. Efficacy tests showed a significant increase in zebrafish weight (p < 0.05), with F3 yielding the best results. A high survival rate (≥80%) suggests the formulation is relatively safe. In conclusion, California papaya leaf extract capsules demonstrate significant potential as an agent to promote weight gain.
Analisis Faktor Risiko Indeks Massa Tubuh, Riwayat Hipertensi, dan Riwayat Preeklampsia terhadap Kejadian Preeklampsia pada Ibu Hamil
Preeclampsia is a pregnancy complication that significantly contributes to maternal and neonatal morbidity and mortality worldwide. Globally, it affects approximately 3–8% of pregnancies and causes more than 70,000 maternal deaths each year. In Indonesia, preeclampsia accounts for around 30% of the 4,151 maternal deaths reported in 2024. In Padang City, there were 254 cases in 2023 and 129 cases in 2024, with Puskesmas Bungus having the highest prevalence (7.2% and 3.77%). This study aimed to analyze the association between body mass index (BMI), history of hypertension, and history of preeclampsia with the incidence of preeclampsia among pregnant women at Puskesmas Bungus, Padang. This study used a quantitative case-control design involving 50 cases and 50 controls. Data were analyzed using chi-square and logistic regression tests. The results showed significant associations between obesity (p=0.031; OR=2.897), history of preeclampsia (p=0.006; OR=13.821), and history of hypertension (p=0.002; OR=17.216) with the incidence of preeclampsia. Multivariate analysis identified history of hypertension as the most dominant factor associated with preeclampsia. This study concludes that obesity, history of hypertension, and history of preeclampsia are significant risk factors for preeclampsia among pregnant women. Strengthening early detection and routine antenatal care for high-risk pregnancies is necessary to reduce maternal complications associated with preeclampsia.
Efektivitas intervensi K3 Melalui Edukasi APD terhadap peningkatan Keselamatan Kerja pada Pekerja TKBM di Pelabuhan Tenau
Keamanan dan kesehatan di tempat kerja adalah salah satu hal penting dalam membentuk suasana kerja yang aman, terutama bagi pekerja bongkar muat (TKBM) yang menghadapi risiko kecelakaan kerja yang cukup besar. Pemakaian Alat Pelindung Diri (APD) yang memenuhi standar merupakan salah satu langkah untuk mencegah terjadinya kecelakaan kerja di area pelabuhan. Namun, hasil pengamatan di Pelabuhan Tenau menunjukkan masih ada pekerja yang mengenakan APD tidak sesuai standar SNI dan tidak menggunakan APD secara lengkap saat bertugas. Studi ini bertujuan untuk mengevaluasi dampak pendidikan penggunaan APD terhadap pengetahuan keselamatan kerja pada pekerja bongkar muat (TKBM) di Pelabuhan Tenau. Penelitian ini mengaplikasikan metode kuantitatif dengan desain pre-eksperimental yang menggunakan pendekatan one group pre-test dan post-test. Sampel penelitian terdiri dari 28 responden dengan alat penelitian berupa kuesioner yang berisi 10 pertanyaan. Hasil penelitian menunjukkan bahwa sebelum mendapatkan edukasi, rata-rata responden berhasil menjawab dengan benar 6 pertanyaan (60%) dan memberikan jawaban salah pada 4 pertanyaan (40%). Setelah mendapatkan edukasi, hasil post-test menunjukkan peningkatan pengetahuan di mana sebagian besar responden dapat menjawab dengan benar sebanyak 9 pertanyaan (90%) dan jawaban salah berkurang menjadi 1 pertanyaan (10%). Berdasarkan hasil studi, dapat disimpulkan bahwa pelatihan penggunaan APD berdampak pada peningkatan pengetahuan keselamatan kerja bagi tenaga kerja bongkar muat (TKBM). Sehingga, diperlukan pengawasan dan pendidikan secara berkala mengenai pemakaian APD yang memenuhi standar SNI untuk meningkatkan keselamatan kerja di area pelabuhan.
Hubungan Kepatuhan Menggunakan Alat Pelindung Diri dengan Imunoglobulin E (IgE) Total pada Pekerja Industri Textil
Chemical exposure during the dyeing process in the Textile industry has the potential to cause health problems, particularly allergic reactions mediated by Immunoglobulin E (IgE). Non-compliance with the use of Personal Protective Equipment (PPE) may increase the risk of chemical exposure through inhalation and skin contact, thereby triggering an allergic immune response characterized by elevated total IgE levels in the blood. This study aimed to determine the relationship between compliance with the use of Personal Protective Equipment (PPE) and total Immunoglobulin E (IgE) levels among Textile industry workers. This research was an analytic observational study with a cross-sectional design. The sample consisted of 15 Textile industry workers who met the inclusion and exclusion criteria, selected using purposive sampling technique. Data on PPE compliance were obtained through questionnaires and interviews, while total IgE levels were measured using the Electrochemiluminescence Immunoassay (ECLIA) method. The relationship analysis was conducted using Fisher’s Exact test. The results showed a significant relationship between PPE compliance and total IgE levels (p<0.05). It can be concluded that there is a significant association between compliance with the use of Personal Protective Equipment and total Immunoglobulin E (IgE) levels among Textile industry workers.
Hubungan Konflik Peran Ganda, Status Pernikahan, Usia, dan Lama Bekerja dengan Stres Kerja pada Pekerja Wanita
Work stress is a critical occupational health concern among midwives working at primary healthcare facilities. This cross-sectional study aimed to analyze factors associated with work stress among 30 midwives, including age, marital status, length of service, and dual-role conflict. Data were collected using structured questionnaires measuring work stress (9 valid items) and dual-role conflict (6 items), and analyzed through univariate, bivariate (Fisher's Exact Test and Chi-Square), and multivariate (binary logistic regression) analyses. Results showed that 43.3% of midwives experienced high work stress and 53.3% reported high dual-role conflict. Bivariate analysis revealed significant associations between work stress and marital status (p=0.009) and dual-role conflict (p=0.004), while age (p=0.633) and length of service (p=0.586) were not significant. Multivariate analysis identified dual-role conflict as the primary determinant of work stress (OR=15.762; 95% CI: 2.149–115.631; p=0.007). Healthcare facility management should develop gender-responsive policies and workplace stress intervention programs to reduce dual-role conflict and work stress among midwives.
Gambaran Kejadian Persalinan pada Ibu dengan Preeklampsia di RSUD Dr. Soeselo Slawi Kabupaten Tegal
Preeclampsia is one of the leading causes of maternal mortality and may result in various complications during pregnancy and childbirth. In Tegal Regency, preeclampsia contributed to 27% of maternal deaths in 2024; therefore, studies on childbirth characteristics among mothers with this condition are needed. This study aimed to identify the characteristics of childbirth events in mothers with preeclampsia at Dr. Soeselo Slawi Regional Hospital, Tegal Regency. A descriptive design with a retrospective approach was used by reviewing the medical records of 202 mothers who delivered with preeclampsia during 2025. Data were analyzed univariately and presented as frequency distributions and percentages. The results showed that most mothers underwent operative delivery (62.38%), while spontaneous and induced labor accounted for 37.13% and 0.50%, respectively. Most deliveries occurred at preterm gestational age (62.38%), followed by term (36.14%) and postterm (1.49%) deliveries. Maternal and obstetric complications included bleeding (6.93%), fetal distress (4.95%), eclampsia (1.49%), and HELLP syndrome (0.99%). Most neonates had normal birth weight (82.18%) and did not require NICU care (95.05%), although low birth weight (17.82%) and NICU admission (4.95%) were still identified. The maternal clinical condition was dominated by blood pressure of 140–159/90–109 mmHg (75.74%). Proteinuria was found in 46.53% of respondents, with moderate proteinuria (+2) as the predominant category (38.30%). In conclusion, childbirth among mothers with preeclampsia was dominated by operative and preterm deliveries. These findings emphasize the importance of early detection and optimal management of preeclampsia to reduce maternal and neonatal complications and improve the quality of maternal-infant health services overall.
Analisis Pengaruh Gaya Kepemimpinan Transformasional terhadap Komitmen Organisasi dan Organizational Citizenship Behavior (OCB) pada Perawat di Rumah Sakit X
Having employees with OCB attitudes will have a positive impact on the ease of achieving organizational goals. OCB is the attitude of employees doing many things outside of their duties voluntarily. In contrast, OCB will influence each other with organizational commitment. Organizational commitment is a person's sense of comfort in being part of the organization. The growth of these two things is influenced by the leadership style, in this case, the transformational leadership style. Based on the preliminary survey results, it has been shown that OCB attitudes and organizational commitment are both influenced by leadership style. So, the researcher wants to see the effect of the three. This study uses multiple linear regression research with quantitative research and a questionnaire with a Likert scale. After the analysis had been conducted, the results were H1: Transformational Leadership had a significant effect on Organizational Citizenship Behavior (OCB) in X Hospital nurses, H2: Transformational Leadership has a substantial impact on organizational commitment in X Hospital nurses, and H3: Organizational Commitment had a significant effect on Organizational Citizenship Behavior (OCB) on nurses at Hospital X.
Formulasi dan Uji Aktivitas Sediaan Krim Antioksidan Ekstrak Daging Buah Rumbiah (Metroxylon Sagu Rottb)
Rumbia fruit contains various bioactive secondary metabolites, particularly flavonoids, which are recognized for their antioxidant properties. These compounds contribute to the prevention of oxidative damage by scavenging and neutralizing free radicals. To enhance its practicality and ease of application, the fruit pulp extract was incorporated into a cream formulation. This study aimed to develop a topical cream containing rumbia fruit pulp extract and to evaluate its physicochemical characteristics. The antioxidant activity of the formulated cream was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. The results demonstrated that the extract could be successfully formulated into a stable cream preparation. Furthermore, the formulated cream complied with the quality requirements for topical creams, as evidenced by satisfactory organoleptic properties, homogeneity, pH value, spreadability, and adhesiveness. Antioxidant evaluation revealed a color transition from purple to yellow during the DPPH assay, indicating the ability of the extract to scavenge free radicals and exhibit antioxidant activity.
Identification of Stunting Risk Based on Maternal Prenatal Factors Using Random Forest Approach: A Preliminary Retrospective Study
Stunting is a multifactorial public health problem influenced by various risk factors that may emerge during the prenatal period. Early identification of stunting risk during pregnancy is important to support preventive interventions. This study aimed to develop a stunting risk prediction model based on maternal prenatal factors using the Random Forest algorithm. Secondary data from 172 pregnant women, consisting of 83 stunting cases and 89 non-stunting cases, were analyzed. The predictor variables included maternal age during pregnancy, height, hemoglobin level, mid-upper arm circumference (MUAC), smoking history, hypertension, asthma, and diabetes mellitus. The research stages consisted of data preprocessing, model training using Stratified 5-Fold Cross Validation, performance evaluation, external testing, and feature importance analysis. Internal evaluation results showed an accuracy of 60%, precision of 60.6%, recall of 57.3%, F1-score of 58.9%, and AUC of 0.6688. External testing yielded an accuracy of 70% and an AUC of 0.6167. Feature importance analysis identified maternal age during pregnancy as the most influential variable in the prediction process. The findings indicate that maternal prenatal factors have potential for early stunting risk identification, although the predictive performance remains moderate. This approach may serve as a foundation for developing early screening tools to support targeted interventions among high-risk pregnancies.
Optimalisasi Perkembangan Kognitif Anak Usia Dini melalui Pola Asuh Orang Tua : Tinjauan Naratif
Cognitive development is an important aspect of early childhood growth because it forms the foundation for children’s abilities to think, remember, understand concepts, solve problems, and make decisions. Early childhood is often referred to as the golden age since development occurs very rapidly during this period, requiring appropriate stimulation from the surrounding environment, particularly the family. In this context, parents play a crucial role through the parenting styles they apply in daily life. This study aims to examine the relationship between parenting styles and early childhood cognitive development based on findings from previous research. The method used is a narrative review by analyzing relevant scholarly articles published between 2020 and 2026. Articles that met the inclusion criteria were then analyzed descriptively to identify the relationship between parenting styles and children’s cognitive development. The results of the review of 15 selected articles indicate that there is a significant relationship between parenting styles and early childhood cognitive development. Authoritative parenting emerged as the most consistently positive style, characterized by effective communication, emotional support, balanced supervision, and opportunities for children to develop independent thinking skills. Other factors, such as parents’ educational level, involvement in children’s learning activities, and a supportive learning environment, also contribute to cognitive development. In conclusion, authoritative parenting is considered the most effective approach in supporting optimal cognitive development in early childhood.
Pengaruh Pemberian Air Rebusan Daun Kelor terhadap Kadar Glukosa Darah pada Penderita Diabetes Melitus di Kelurahan Padaleu Kecamatan Kambu, Kendari
Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels due to impaired insulin secretion, insulin action, or both. Uncontrolled diabetes can lead to various complications and decreased quality of life. Moringa oleifera leaves contain bioactive compounds, including flavonoids, vitamins A, C, and E, as well as selenium, which possess antioxidant properties and are believed to help reduce blood glucose levels. This study aims to determine the effect of Moringa leaf decoction on reducing blood glucose levels in patients with diabetes mellitus in Padaleu Village, Kambu District, Kendari City. The study employs a quantitative pre-experimental design using a one-group pretest-posttest approach. The population consists of 35 diabetes mellitus patients, with 17 respondents selected through purposive sampling. Blood glucose levels are measured before and after the administration of Moringa leaf decoction using a glucometer and observation sheets. Respondents receive 200 ml of Moringa leaf decoction daily for five consecutive days. Data analysis is conducted using paired statistical tests to determine differences in blood glucose levels before and after the intervention. The findings of this study are expected to provide scientific evidence regarding the effectiveness of Moringa leaf decoction as a non-pharmacological therapy for controlling blood glucose levels among diabetes mellitus patients. Furthermore, the results may contribute to nursing science development and serve as a reference for healthcare providers and future researchers in implementing complementary therapies for diabetes management.
Etiologi Multifaktorial dan Tantangan Diagnostik Disfagia pada Pasien Geriatri Usia Sangat Lanjut : Laporan Kasus dan Tinjauan Skoping
Dysphagia in extremely elderly patients represents a significant clinical challenge because it is frequently associated with frailty, malnutrition, and an increased risk of aspiration. Multifactorial etiologies and atypical clinical manifestations may complicate diagnosis and delay appropriate management. This study aimed to describe the diagnostic evaluation and clinical findings of dysphagia in an extremely elderly patient through a case report supported by a scoping review. A 105-year-old woman with chronic progressive dysphagia underwent comprehensive assessment, including physical examination, upper gastrointestinal endoscopy, histopathological evaluation, and chest radiography. Relevant literature on dysphagia in geriatric populations was reviewed to provide contextual understanding of diagnostic challenges and underlying etiologies. The evaluation revealed chronic active gastritis and a hamartomatous polyp in the gastroesophageal region without evidence of malignancy. Comprehensive assessment successfully excluded malignant and acute obstructive causes, emphasizing the complexity of dysphagia diagnosis in extremely elderly individuals with frailty and aspiration risk. These findings underscore the importance of endoscopic and histopathological examinations in distinguishing benign from malignant etiologies and support early recognition of multifactorial non-malignant causes to optimize clinical management and reduce the risk of adverse outcomes in this vulnerable population
Pengaruh Role Playing dan Simulasi untuk Gawat Darurat (RANGGA) terhadap Pengetahuan dan Keterampilan Kegawatdaruratan Tim UKS Anak Sekolah
The risk of accidents in the school environment is quite high, but the ability of the School Health Business Team (UKS) to handle emergencies is often still limited to theoretical knowledge without adequate practical skills. This study aims to analyze the influence of the Role Playing and Emergency Simulation (RANGGA) method on the improvement of the knowledge and skills of the UKS Team in junior high school. This study used a quasi-experiment design with a pre-post test with control group design. The research sample amounted to 60 respondents which were taken by purposive sampling technique. The intervention group was given RANGGA training, while the control group was given conventional education. The data were analyzed using the non-parametric Wilcoxon Signed Ranks Test because the data distribution was abnormal. In the intervention group, there was an increase in the average knowledge score from 88.7 to 97.9 and the skill score from 87.99 to 97.98. The results of the Wilcoxon test showed a significance value of p<0.001 for both variables in the intervention group, indicating a very strong influence of the RANGGA method. In contrast, although the control group experienced an improvement, the variation in scores remained higher and the improvement was not as significant as the intervention group. The RANGGA method is significantly effective in improving the emergency competence of the UKS Team through an experiential learning approach. It is recommended for school institutions to integrate simulation and role play methods in the UKS training curriculum to ensure optimal emergency response readiness.
Efektivitas Kompres Hangat terhadap Intensitas Dismenorea pada Remaja Perempuan: Sebuah Studi Quasi-Eksperimental
Primary dysmenorrhea frequently disrupts the academic and daily activities of adolescent girls. This study evaluated the effectiveness of a 5-minute warm compress application in reducing menstrual pain intensity. A quasi-experimental study with a one-group pretest-posttest design was conducted on 42 female students of SMAN 28 Batam selected through purposive sampling. Participants applied a warm compress (40–45 °C) to the lower abdomen for 5 minutes. Pain intensity was measured using the Numeric Rating Scale (NRS) before and after the intervention. Data were analyzed using the Wilcoxon Signed-Rank test. Before the intervention, 42.9% of participants reported severe pain (NRS 7–10). After the 5-minute application, the severe pain category disappeared entirely (0%), with 57.1% of subjects shifting to the mild pain category (NRS 1–3). Statistical analysis showed a significant reduction in dysmenorrhea intensity (p < 0.001). A 5-minute warm compress application is a rapid and effective non-pharmacological intervention for relieving primary dysmenorrhea in adolescents. Its practicality makes this method a feasible self-care strategy to implement in school settings.
Tinjauan Naratif Transformasi Digital dalam Manajemen Rumah Sakit di Indonesia Periode Tahun 2020-2025
In order to raise the standard of healthcare services in the contemporary period, digital transformation in hospital management has become a phenomena. The purpose of this study is to investigate the adoption, advantages, difficulties, and success aspects of digital transformation in healthcare facilities. A literature review employing a narrative review system was the methodology. 14 papers that met the inclusion requirements were found using data sources from Google Scholar, PubMed, and ScienceDirect databases with publication years ranging from 2020 to 2025. To determine the primary study themes, data analysis was carried out utilising a thematic synthesis approach. According to the study's findings, digital transformation can enhance operational effectiveness, service quality, and patient safety by using technology including electronic health records (EHR), telemedicine, and hospital management information systems. However, there are still a number of obstacles to its adoption, such as inadequate infrastructure, inadequate human resource competency, expensive investment costs, and data security threats. Significant barriers also include a lack of system integration and opposition to change. Government policies and regulatory assistance have an impact on the success of digital transformation in hospital administration.